CLINICAL TRIALS AND OBSERVATIONS Management of bleeding in acquired hemophilia A: results from the European Acquired Haemophilia (EACH2) Registry
نویسندگان
چکیده
1Thrombosis and Hemostasis Unit, Ospedale Niguarda, Milan, Italy; 2Arthur Bloom Haemophilia Centre, University Hospital of Wales, School of Medicine, Cardiff University, Cardiff, United Kingdom; 3SRH Kurpfalzkrankenhaus Heidelberg GmbH and Hemophilia Center, Heidelberg, Germany; 4Department of Internal Medicine, Rouen University Hospital, Rouen Cedex, France; 5Unidad de Hemostasia y Trombosis, Servicio de Hematología, Hospital General Universitario, Alicante, Spain; 6National Hemophilia Center and Hemostasis Department, State Health Center, Budapest, Hungary; 7Unit of Biostatistics, Department of Clinical Pharmacology and Epidemiology, Consorzio Mario Negri Sud, Santa Maria Imbaro (Chieti), Italy; 8Clinical Coagulation Research Unit, Skåne University Hospital, Malmö, Sweden; and 9Medical University of Vienna, Department of Medicine 1, Division of Hematology and Hemostasis, Vienna, Austria
منابع مشابه
CLINICAL TRIALS AND OBSERVATIONS Acquired hemophilia A in the United Kingdom: a 2-year national surveillance study by the United Kingdom Haemophilia Centre Doctors’Organisation
1University Hospital of Wales and School of Medicine, Cardiff University, United Kingdom; 2Manchester Royal Infirmary, Manchester, United Kingdom; 3Addenbrookes Hospital, Cambridge, United Kingdom; 4Queen’s Medical Centre, Nottingham, United Kingdom; 5Royal Victoria Infirmary, Newcastle, United Kingdom; 6Hallamshire Hospital, Sheffield, United Kingdom; 7Oxford Haemophilia Centre, United Kingdom...
متن کاملCLINICAL OBSERVATIONS, INTERVENTIONS, AND THERAPEUTIC TRIALS Treatment of acquired hemophilia by the Bonn-Malmö Protocol: documentation of an in vivo immunomodulating concept
Acquired hemophilia (AH) is an extremely rare condition in which autoantibodies (inhibitors) against clotting factor VIII induce acute and life-threatening hemorrhagic diathesis because of abnormal blood clotting. The mortality rate of AH is as high as 16%, and current treatment options are associated with adverse side effects. We investigated a therapeutic approach for AH called the modified B...
متن کاملCLINICAL TRIALS AND OBSERVATIONS Progression to end-stage liver disease in patients with inherited bleeding disorders and hepatitis C: an international, multicenter cohort study
1Van Creveldkliniek, University Medical Center Utrecht, The Netherlands; 2Sheffield Haemophilia and Thrombosis Centre, Sheffield, United Kingdom; 3Haemophilia Centre and Haemostasis Unit, Royal Free Hospital, London, United Kingdom; 4Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, The Netherlands; 5Department of Hepatology and Gastroenterology, University ...
متن کاملRegular Article CLINICAL TRIALS AND OBSERVATIONS Factor VIII brand and the incidence of factor VIII inhibitors in previously untreated UK children with severe hemophilia A, 2000-2011
Department of Haematology, University Hospital of Wales, School of Medicine, Cardiff, United Kingdom; The UK National Haemophilia Database, Manchester, United Kingdom; Department of Haematology, Royal Hospital for Sick Children, Glasgow, United Kingdom; The Haemophilia Centre, The Royal London Hospital, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, Unit...
متن کاملCLINICAL TRIALS AND OBSERVATIONS Mortality rates and causes of death among all HIV-positive individuals with hemophilia in Canada over 21 years of follow-up
Many individuals with hemophilia were infected with human immunodeficiency virus (HIV) in the early 1980s through contaminated blood products. Most also were co-infected with hepatitis C virus (HCV). Deaths among the entire cohort of HIV-positive hemophiliacs in Canada up to 2003 are described. Using registry data, we analyzed Kaplan-Meier survival curves, determined the effect of age at HIV se...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
دوره شماره
صفحات -
تاریخ انتشار 2012